In the latest release of APEX 4.0 (available on tryapexnow) I noticed two nice new features. First of all, on the far right side of the Home page of the builder, there is a little region called "Available Updates". If you click on the little "i" in the upper right of that region, you'll navigate to another page where you can control if you want to check for those updates. Wonder what will happen if I set it to "No"...will it be switched of for just my workspace or for the whole APEX instance? To me it seems it should be an "Administration" kind of functionality - so instance wide. In the "Help" it says: "This attribute controls if Application Express should check if updates are available for Oracle Application Express and the Oracle Application Express Listener. Note: To perform this check Application Express transmits the version number of Application Express and other system components to Oracle Corporation." This seems like a nice functionality to get a sort of alert if there is a patch available. I don't know if you need a Metalink account to enable this feature.
The second one is a "Set Screen Reader Mode On" link at the bottom. If you click that a SET_SESSION_SCREEN_READER_ON is added to the URL of the Builder. I assume that this means that all HTML rendered can be read by a screen reader like JAWS to enhance the accessibility of APEX for visually impaired developers.
I inspected the HTML source of that page before and after that setting and it seems that nothing has changed. Maybe because all rendered HTML is already "screen reader ready"?